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Albert-Ludwigs-Universität Freiburg

Chemistry & Physics of Interfaces
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New DFG funded project on DNA chip platform

The Deutsche Forschungsgemeinschaft (DFG) recently granted funds for a collaborative effort towards the development of a robust DNA chip technology for routine DNA analysis. The project is entitled:

Development of a biochip technology platform for simultaneous gene expression and mutation analysis

The project is headed by CPI (Prof. J. Rühe and Dr. T. Brandstetter), collaborators are Prof. H. Wieland, PD Dr. E. Stickeler and Prof. A. Zur Hausen (all at University Hospital Freiburg).

The basis of the platform is a combination of surface chemistries for the generation of DNA microarrays on plastic chips developed at CPI with a novel ATR based chip read-out system. The partners from the University hospital will provide samples for analysis and are responsible for reliability tests and cross checks. As a first analytical problem we will work on the development of a chip system for the determination of breast cancer.

Our picture shows a DNA chip mounted to a ATR cell prototype:

Further information can be obtained from:

Prof. Dr. Jürgen Rühe or Dr. Thomas Brandstetter

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